scFvright

scFv intrabody solubility from amino acid sequence


scFvright predicts the solubility of a single chain variable fragment (scFv) on expression as an intracellular antibody (intrabody).

You can input paired variable domain, scFv with or without modifications or full-length antibody sequences.

scFvright will return the percentage likely to be found in soluble form following expression in mammalian cells.

This is a beta version, please report any bugs.

Select processing method:




Paste your sequence data in FASTA format above, and hit the submit button below.

Depending on the number of sequences you submit, processing may take time (2000 sequences per minute).

Please get in touch if you would like help turning your antibody sequence data into soluble and functional intrabodies.


Confidentiality: Sequences are confidential, not written to disk or saved.


Contact: gareth.wright@essex.ac.uk

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